Pharmacy Times – January 2017

Drug Interactions: Insights and Observations

Does Linezolid Interact with Warfarin?

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD

References.

1. Stalker DJ, Jungbluth GL. Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial. Clin Pharmacokinet. 2003;42:1129-1140.

2. Sakai Y, Naito T, Arima C, Miura M, Qin L, Hidaka H, Masunaga K, Kakuma T, Watanabe H. Potential drug interaction between warfarin and linezolid. Intern Med. 2015;54:459-464.

3. Kinoshita S, Wada, K, Matsuda S, Kuwahara T, Sunami H, Sato T, Seguchi O, Yanase M, Nakatani T, Takada M. Interaction between warfarin and linezolid I patients with left ventricular assist system in Japan. Intern Med. 2016;55:719-724.