Pharmacy Times – Sept 2014

Drug Interactions: Insights and Observations

Extrapolating Pharmacokinetic Data to the Clinical Situation

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD

Reference:

1. Hammond KP, Nielsen C, Linnebur SA, et al. Priapism induced by boceprevir-CYP3A4 inhiibtion and alpha-adrenergic blockade: case report. Clin Infect Dis. 2014;58:e35-e38.

2. Horn JR, Hansten PD, Chan L-N. Proposal for a New Tool to Evaluate Drug Interaction Cases. Ann Pharmacotherapy. 2007;41:674-680.