Experience the thrill of the poker table from the comfort of your home! Join our safe and secure online poker platform, where you can play anytime. Register an IDN Poker acount of your own at Nirwanapoker website now and start your adventure!

The data macau 4d reflects the history of the numbers drawn and can be analyzed to reveal specific patterns of Macau Prize winner number. If you're observant, you'll notice frequent number combinations or identical numbers appearing within a specific time frame. With a comprehensive data source, the website that provides them is a useful option. With a simple interface and daily updates, players can instantly check the latest results of Toto Macau loterry.

Pharmacy Times – June 2014

 

Drug Interactions: Insights and Observations

 

Statins and OATP Interactions

 

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD

 

 

References

 

1. Horn JR and Hansten PD. Be on the alert for increasing drug interactions with statins. Pharmacy Times. 2006;72(June):20.

2. Niemi M et al. Organic anion transporting polypeptide 1b1: a genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev. 2011;63:157-81.

3. Ichimaru N et al. Changes in lipid metabolism and effect of simvastatin in renal transplant recipients induced by cyclosporine or tacrolimus. Atherosclerosis. 2001;158:417-423.

4. Pasanen MK et al. SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid. Pharmacogenet Genomics. 2006;16:873-879.

5. Backman JT et al. Plasma concentrations of active simvastatin acid are increased by gemfibrozil. Clin Pharmacol Ther. 2000;68:122-129 ().

6. The SEARCH collaborative group. SLCO1B1 variants and statin-induced myopathy – a genome wide study. New Engl J Med.2008;359:789-99.

7. Whitfield LR et al. Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin. J Clin Pharmacol. 2011;51:378-388.