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Is Acetaminophen a Problem in Hypertensive Patients?

May 2014

John R. Horn, PharmD, FCCP and Philip D. Hansten, PharmD

References.

1. Horn JR, Hansten PD. Coadministration of NSAIDs and Antihypertensive Agents. Pharmacy Times, April 2006, p. 54.

2. Horn JR, Hansten PD. Diuretics, ACEIs, ARBs, and NSIADs: A Nephrotoxic Combination. Pharmacy Times, April 2013, p. 40.

3. Gualtierotti R, et al. Effect of naproxen and acetaminophen on blood pressure lowering by ramipril, valsartan and aliskiren in hypertensive patients. Expert Opin. Pharmacother. 2013;14:1875-1884.

4. Sudano I, et al. Acetaminophen increases blood pressure in patients with coronary artery disease. Circulation. 2010;122:1789-1796.