The 2018 edition of The Top 100 Drug Interactions includes several hundred new drug-drug
interactions and monographs. As in the past, we have included interactions that may produce clinically
important adverse events based on their properties to assist you in predicting interactions were limited
data are available. The table of CYP450 and drug transporter substrates and modifiers now includes
over 525 drugs. In addition, many of the existing monographs have been revised to reflect newly
published data. Interaction entries are easy to find in the index by either trade or generic name. The
Horn and Hansten Drug Interaction Probability Scale is included to assess the probability of a causal
relationship between a potential drug interaction and a patient event. The Top 100 Drug Interactions is
an authoritative drug interaction resource intended for all practitioners that fits in your pocket (8.5 x 5.5
inches).
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